A 2016 study identified a “characteristic chemical signature” in chronic fatigue sufferers who had underlying biology similar to the state of dauer. Like hibernation, dauer is a way of keeping you alive by severely limiting functions of ordinary life such as energy, digestion, and movement. A 2017 study by Davis and Jose Montoya found evidence of a hyper-inflammatory response. Davis wrote, “There’s been a great deal of controversy and confusion surrounding ME/CFS – even whether it is an actual disease… Our findings show clearly that it’s an inflammatory disease and provide a solid basis for a diagnostic blood test.” Apparently, the immune system can be stimulated by an unknown cause and then enters a complete abnormal fight mode, activating a hyper-inflammatory response which can continue even after the initial trigger has been resolved. This problem can be resolved by taking an anti-inflammatory remedy like CBD oil.